Skip to main content
. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Bioconjug Chem. 2012 Aug 2;23(8):1694–1703. doi: 10.1021/bc300244a

Figure 1.

Figure 1

TEM images of a) TMV1cys-Tn1 and b) TMV1cys-Tn4 confirming that TMV was still intact after Tn conjugation. c) MALDI-TOF MS spectra of the monomer units of TMV1cys, TMV1cys-Tn1, TMV1cys-alkyne, and TMV1cys-Tn4. The ion intensity ratio of the peaks corresponding to Tn functionalized monomer of TMV1cys-Tn1 (m/z = 18,142) and the underivatized monomer (m/z = 17,638) was 1: 4, suggesting approximately 450 of the possible 2330 Cys 3 sites were derivatized. Analogously, it was determined that on average 1530 Tn antigens were attached on each TMV1cys-Tn4 capsid.