Table 3.
Clinical symptoms at diagnosis, reported for 5% or more of all patients with confirmed pulmonary hypertension (PH confirmed), according to pulmonary hypertension groups and subgroups
| All PH confirmed | PH group 3 | PH group 1 | ||||||
|---|---|---|---|---|---|---|---|---|
| IPAH or FPAH | APAH with congenital heart disease | APAH excluding APAH with CHD | ||||||
| All CHD | Unrepaired shunt* | Repaired shunt | Never shunt | |||||
| Patients | 362 (100%) | 42 (100%) | 182 (100%) | 115 (100%) | 61 (100%) | 45 (100%) | 9 (100%) | 20 (100%) |
| Dyspnoea with exertion | 235 (65%) | 22 (52%) | 121 (66%) | 77 (67%) | 48 (79%) | 24 (53%) | 5 (56%) | 14 (70%) |
| Fatigue | 149 (41%) | 12 (29%) | 82 (45%) | 47 (41%) | 29 (48%) | 13 (29%) | 5 (56%) | 6 (30%) |
| Syncope | 73 (20%) | 3 (7%) | 57 (31%) | 10 (9%) | 0 (0%) | 8 (18%) | 2 (22%) | 3 (15%) |
| Cyanosis with exertion | 64 (18%) | 10 (24%) | 24 (13%) | 27 (23%) | 22 (36%) | 5 (11%) | 0 (0%) | 3 (15%) |
| Cough | 48 (13%) | 6 (14%) | 32 (18%) | 8 (7%) | 1 (2%) | 7 (16%) | 0 (0%) | 2 (10%) |
| Cyanosis with rest | 44 (12%) | 11 (26%) | 7 (4%) | 22 (19%) | 15 (25%) | 4 (9%) | 3 (33%) | 4 (20%) |
| Dyspnoea with rest | 39 (11%) | 12 (29%) | 13 (7%) | 11 (10%) | 3 (5%) | 6 (13%) | 2 (22%) | 3 (15%) |
| Chest pain or discomfort | 39 (11%) | 3 (7%) | 24 (13%) | 7 (6%) | 4 (7%) | 2 (4%) | 1 (11%) | 4 (20%) |
| Near-syncope | 28 (8%) | 1 (2%) | 21 (12%) | 5 (4%) | 1 (2%) | 4 (9%) | 0 (0%) | 1 (5%) |
| Dizziness | 25 (7%) | 2 (5%) | 14 (8%) | 6 (5%) | 4 (7%) | 2 (4%) | 0 (0%) | 2 (10%) |
| Palpitations | 22 (6%) | 0 (0%) | 12 (7%) | 6 (5%) | 6 (10%) | 0 (0%) | 0 (0%) | 3 (15%) |
| Pallor with exertion | 17 (5%) | 3 (7%) | 8 (4%) | 5 (4%) | 5 (8%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Irritability | 17 (5%) | 5 (12%) | 8 (4%) | 3 (3%) | 2 (3%) | 1 (2%) | 0 (0%) | 1 (5%) |
Data are number (%). Patients from pulmonary hypertension groups 4 and 5 (n=3), included in all patients with confirmed pulmonary hypertension, are not depicted separately in this table. Full details are provided in the webappendix. APAH=pulmonary arterial hypertension associated with other disorders. IPAH=idiopathic pulmonary arterial hypertension. FPAH=familial pulmonary arterial hypertension. CHD=congenital heart disease.
*
Or partial repair.