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. Author manuscript; available in PMC: 2013 Jul 17.
Published in final edited form as: Dev Cell. 2012 Jul 17;23(1):11–20. doi: 10.1016/j.devcel.2012.06.012

Table 2.

Bioinformatic analysis of the abundance of consensus CBMs in mouse and yeast proteinsa

Number of
proteins		 Number
containing CBM		 Overall
percentage
(%)
Mouse
Full length proteinsb 33451 10076 30
Cytoplasmic sequencesc
      Soluble 22265 5936 27
      Type I transmembrane 1548 201 13
      Type II transmembrane 2869 335 12
      Multi-pass transmembrane 3821 739 19
      Total 30503 7211 24
Non-cytoplasmic sequencesc
      Soluble 2948 996 34
      Type I transmembrane 1548 488 32
      Type II transmembrane 2869 608 21
      Multi-pass transmembrane 3821 773 20
      Total 11186 2865 26
Yeast
All proteins 6736 2883 43
a

Sequences derived from CYGD database http://mips.helmholtz-muenchen.de/genre/proj/yeast/ were scanned for the presence of any of the two putative CBM sequences; ΩxΩxxxxΩ and ΩxxxxΩxxΩ or the combined consensus sequence ΩxΩxxxxΩxxΩ (Couet et al., 1997), where Ω is either Phe, Trp or Tyr.

b

The full set of 51135 coding sequences was reviewed, and those with annotated truncations at the N-terminus were discarded: topology with respect to the membrane cannot be accurately determined in this set.

c

Topology with respect to the membrane was calculated based on the presence in sequences of signal peptides and integral membrane domains using a previously published annotation pipeline (Davis et al., 2006).