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Distribution of non-interacting residues with PB change. A). Histogram of “% of ‘residues nearby interface’ in a protein undergoing PB change” is plotted. B). Histogram of “% of non-interacting residues with PB change” which are near to interface is plotted. The upper-bound value for every range is indicated as the label on x-axis. This figure reveals that most of the conformational changes occurring in the non-interacting surface regions are not near the interface.
