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. 2012 Aug 3;109(34):13644–13649. doi: 10.1073/pnas.1207170109

Table 1.

Half maximal inhibitory concentrations (IC50) for Hh pathway (in μM)

SA1 SA2 SA3 SA4 SA5 SA6 SA7 SA8 SA9 SA10 CA1 Cyclopamine
Shh-LIGHT2 cells (Gli-luciferase) 3.1 12 1.2 0.92 5 9.2 5.8 18 19 5 >25 0.9
Ptch1−/− fibroblast (β-gal) 3.8 9.9 20 1.3 25 7.3 3.2 19 1 11 >25 0.15