Table 1. Effects of G-CSF on mobilized bone marrow cells in the peripheral blood.

Hours afterCCI surgery	0	3		6		12		24		48		72		144
Groups	Naïve	CCI+vehicle	CCI+G-CSF	CCI+vehicle	CCI+G-CSF	CCI+vehicle	CCI+G-CSF	CCI+vehicle	CCI+G-CSF	CCI+vehicle	CCI+G-CSF	CCI+vehicle	CCI+G-CSF	CCI+vehicle	CCI+G-CSF
Total WBCs	4.72 (0.23)	6.04 (0.73)	10.73 (1.06)*	6.45 (0.81)	11.11 (1.02)*	8.72 (2.03)	15.76 (2.22)*	6.84 (0.82)	13.95 (1.19)*	6.31 (1.53)	11.29 (0.67)*	5.76 (0.98)	10.88 (3.31)	4.88 (0.75)	5.80 (1.07)
PMNs	4.16 (0.18)	5.18 (0.61)	9.88 (1.10)*	5.18 (0.70)	10.43 (0.99)*	7.81 (2.12)	14.53 (2.36)*	5.85 (0.87)	12.51 (1.21)*	4.71 (1.28)	9.40 (0.64)*	4.41 (1.11)	9.55 (3.24)	3.82 (0.60)	4.48 (0.61)
Lymphocytes	0.41 (0.10)	0.66 (0.13)	0.69 (0.12)	1.04 (0.28)*	0.38 (0.08)	0.58 (0.24)	0.62 (0.35)	0.58 (0.33)	0.80 (0.26)	1.38 (0.53)	1.40 (0.33)	1.09 (0.44)	1.13 (0.88)	1.15 (0.12)	0.99 (0.35)
Monocytes	0.04 (0.02)	0.09 (0.09)	0.08 (0.07)	0.10 (0.06)	0.06 (0.04)	0.08 (0.03)	0.40 (0.28)	0.30 (0.12)	0.41 (0.09)	0.16 (0.21)	0.34 (0.14)	0.15 (0.17)	0.11 (0.22)	0.39 (0.09)	0.21 (0.14)

Compared to vehicle treatment in rats with CCI, G-CSF treatment in rats with CCI significant increased the number of circulating WBCs and PMN cells at 3, 6, 12, 24, and 48 h after CCI. In contrast, the levels of circulating lymphocytes and monocytes at the above-mentioned time points were not significantly different between the G-CSF- and vehicle-treated rats with CCI, except at 6 h when there was a transient increase in the level of lymphocytes in vehicle group. Data are shown as the mean±SEM; n = 6 per group; Mann–Whitney U test, *p<0.05.