Table 3. Studies of vitamin D status in adults with asthma.
| Author | Year | n (% male) |
Age (years) | Study Design | Sample | Outcome Measures | Findings |
|---|---|---|---|---|---|---|---|
| Black80 |
2005 |
14,091 (55) |
> 20 y |
Cross-sectional |
General US population |
Lung function |
Higher serum 25(OH)D associated with increased lung function |
| Keet81 |
2011 |
6857 (49) |
23.6 |
Cross-sectional |
General US population |
Wheeze, history of asthma, and asthma exacerbation |
Higher serum 25(OH)D associated with decreased odds of current wheezing and asthma as well as emergency visits for asthma and asthma exacerbations |
| Li82 |
2011 |
435 (38) |
48.57 |
Cross-sectional |
Newly diagnosed asthmatics |
Lung function, total serum IgE |
Higher 25(OH)D associated with greater lung function with no associations noted for IgE |
| Oren83 |
2008 |
290 (26) |
43 |
Cross-sectional |
Obese patients |
Asthma and allergic rhinitis |
25(OH)D deficiency (< 25 ng/mL) associated with increased odds of atopic dermatitis but no associations with asthma |
| Sutherland84 | 2010 | 54 (43) | 38.3 | Cross-sectional | Persistent asthma | Lung function, airway hyper-responsiveness, glucocorticoid responsiveness | Decreased 25(OH)D associated with decreased lung function, increased airway hyperresponsiveness, and reduced glucocorticoid responses |