Table 2. Correlation of the global DNA methylation measures between sisters discordant for breast cancer by blood cell type, New York site of the BCFR.
Granulocytes | Total White Blood Cells | Pooled Source | |||||||
---|---|---|---|---|---|---|---|---|---|
|
N |
r |
p value |
N |
r |
p value |
N |
r |
p value |
[3H]-methyl acceptance assay (DPM/μg) |
64 |
-0.08 |
0.51 |
134 |
0.24 |
0.006 |
198 |
0.19 |
0.006 |
LUMA (% DNA methylation) | 80 | 0.21 | 0.06 | 155 | 0.13 | 0.10 | 235 | 0.16 | 0.01 |