Figure 5. Wnt pathway repression in TSA-treated MCF7 breast cancer cells. (A) Fold changes in the expression of 84 genes relevant to the Wnt signaling pathway. Fold change in normalized gene expression in the Test Sample (TSA-treated MCF7 cells) divided by the normalized gene expression in the Control Sample (MCF7 cells). The middle line shows similar expression in both groups with 2-fold change boundaries. (B) Pathway activity score for Wnt signaling in experimental samples relative to control samples.