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. 2012 Aug 24;7(8):e37095. doi: 10.1371/journal.pone.0037095

Table 1. Additional mutations in neuraminidase and hemagglutinin.

			Additional mutations in NA^x				Additional mutations in HA^x
A/California/7/2009	H275	I223	G249	N329	K331	T332	D97	D187	I321	E374	F415	I418	N444
A/NewYork/18/2009									V
D0^a
D6	H/Y	I/R									F/L
D11	H/Y	I/R								E^*-E/K^#	F/L
D19	H/Y	I/R								E^*-E/K^#	F^*-F/L^#	I^#-L^*
D25	H/Y	I/R								E^*-E/K^#	F/L	I^*-I/L^#
D45	H/Y	I/R					D^# -D/N^*		I/V	E^*-E/K^#	F/L	L^*- I/L^#
D69	H/Y	I/R	G^*-G/E^#	N	K^*-K/Q^#	T^*-T/A^#			I/V	E^*-E/K^#	F/L	I^*- I/L^#
D83^a		I/R	G^*	D^*	K^*	T^*	D^*	D/N^*	A/V^*	E^*	F^*	L^*	N/K^*
D98^b		I/R	G^*-G/E^#	N/D	K	T^*-T/A^#	N^*	D/N^*	A/V/T/I^*	E^*	F/L^*	L^*	N/K^*

Only amino acid mutations or mixture of wild type and mutations are indicated.

^a

HA and NA sequence only from isolate.

^b

HA sequence only from isolate.

^*

: detected only on isolates.

^#

: detected only on clinical specimens.

^x

: relative to the sequence of A/NewYork/18/2009.