Table 3. Connectivity and fold-changes of key regulatory genes in the co-expression networks of mouse ESCs.
| Gene symbol | Regulator | Fold change | Connectivity in the control | Connectivity in the knockdown |
| Sall4 | TF | 1.165 | 959 | 0 |
| Mybl2 | TF | 4.815 | 867 | 36 |
| Tcf7 | TF | 1.881 | 773 | 0 |
| Lin28 | Post-transcriptional | 2.955 | 763 | 0 |
| Sox2 | TF | 2.409 | 521 | 0 |
| E2f1 | TF | 1.888 | 685 | 211 |
| Eed | Epigenetic | 1.633 | 916 | 471 |
| Smad3 | TF | 1.056 | 468 | 87 |
| Suz12 | Epigenetic | 1.616 | 430 | 213 |
| Phc1 | Epigenetic | 1.732 | 193 | 0 |
| Zfx | TF | 1.464 | 477 | 294 |
| Nanog | TF | 1.778 | 464 | 343 |
| Jmjd2c | Epigenetic | 1.667 | 305 | 223 |
| Oct4 | TF | 2.501 | 682 | 665 |
| Jarid2 | Epigenetic | 1.645 | 0 | 7 |
| Trp53 | TF | 1.766 | 0 | 16 |
| Dnmt3a | Epigenetic | 1.053 | 333 | 352 |
| Stat3 | TF | 1.224 | 0 | 47 |
| Smad1 | TF | 1.239 | 14 | 86 |
| Ctcf | TF | 1.681 | 229 | 326 |
| Tcl1 | TF | 3.490 | 148 | 261 |
| Zfp281 | TF | 1.676 | 38 | 275 |
| Esrrb | TF | 2.172 | 139 | 431 |
| Klf4 | TF | 1.331 | 0 | 293 |
| Jmjd1a | Epigenetic | 1.385 | 631 | 925 |
| Tcf3 | TF | 1.885 | 497 | 806 |
| Rnf2 | Epigenetic | 1.786 | 0 | 392 |
| Ezh2 | Epigenetic | 2.508 | 4 | 404 |
| Dnmt3b | Epigenetic | 2.393 | 204 | 635 |
| c-Myc | TF | 1.095 | 186 | 742 |
Fold changes are calculated as the ratio of expression between control and B-MYB deficient ESCs. Connectivity is the number of connected genes for each gene on the network. Green highlights factors with reduced connectivity, while red indicates factors with enhanced connectivity among genes.