Table 1. AUC in the framework of leave-one-out cross validation schema under different trade-off parameters combination is calculated to confirm that miREFScan is robust to the selection of parameter values.

	0.001	0.01	0.1	1	10	100	1000
0.001	0.9503	0.9576	0.9544	0.9543	0.9516	0.9573	0.9556
0.01	0.9324	0.9597	0.9578	0.9577	0.9550	0.9606	0.9590
0.1	0.9197	0.9387	0.9565	0.9577	0.9550	0.9606	0.9589
1	0.9137	0.9230	0.9388	0.9573	0.9555	0.9611	0.9595
10	0.9107	0.9171	0.9232	0.9464	0.9510	0.9569	0.9553
100	0.9131	0.9193	0.9243	0.9459	0.9518	0.9581	0.9564
1000	0.9121	0.9183	0.9233	0.9446	0.9507	0.9569	0.9552