Figure 3.
Effect of CAPS on HPA stress reactivity in response to acute immobilization stress. A) CAPS-treated rats displayed a blunted ACTH response to a subsequent acute stressor (bar), particularly in the group tested on day 1 post-CAPS. B) There were no significant differences between groups on the acute CORT response to immobilization stress, although there was a modest decrease in the group tested on day 1 post-CAPS. *p < 0.05 1-day post-CAPS vs Controls, *** p < 0.001 1-day post-CAPS vs Controls, +++p < 0.001 1-day post-CAPS vs 5-days post-CAPS. Data expressed as mean ± SEM, n = 7–14/grp.