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. 2012 Sep;92(3):445–459. doi: 10.1189/jlb.0212052

Table 2. Surface marker, tissue distribution, and transcriptional regulators of human DC subsets.

DC subset Surface markers Tissue distribution Transcription factor(s) Referencesa
pDC HLA-DR+CD11cBDCA-2+ BDCA-4+CD123+ Blood, tonsil, lymph nodes E2-2, GATA-2, IRF8, SpiB, PU.1 [99, 216, 221223, 237]
DC
    CD1c+ (BDCA-1+) HLA-DR+CD11c+CD11b+ CD1c+ Blood, tonsil, lymph nodes GATA-2, IRF8 [216, 221223]
    CD141+ (BDCA-3+) HLA-DR+CD11c+CD11b CD141+XCR1+CLEC9A+ Blood, tonsil, lymph nodes GATA-2, IRF8 [216, 221223]
    CD103+ DC-LAMP+CD103+ Mesenteric lymph nodes Unknown NA
    CD1a+ CD11c+CD1a+CD14 Skin, lymph nodes GATA-2, STAT5 [157, 221223]
    CD14+ CD11c+ CD14+ CD1a Skin, lymph nodes GATA-2 [221223]
    LC CD11c+EpCAM+ Skin, skin-draining lymph nodes Unknown NA
Mono/DC
    CD16+ CD11c+CD16+HLA-DR+ Blood GATA-2 [221223]
a

References for transcriptional regulators are provided. References for DC subset identification and localization can be found in the text.