Table 4.

Overview of recent studies on risk factors for recurrence and surgical management of primary GCTB

	A	B	C	D	E	F	G	H	I	J
O’Donnell et al. 1994	Single	60	–	–	–	13/30	–	5/30	–	Pathological fracture, soft tissue extension
Becker et al. 2008	Multi-	256	1/48	32/65	–	15/69	13/50	–	–	Soft tissue extension b
Balke et al. 2008 b	Multi-	214	0/18	32/55	–	19/52	–	7/39	5/42	Soft tissue extension, distal radius a
Kivioja et al. 2008	Multi-	294	11/92	24/47	–	32/147	–	–	–	Age b
Klenke et al. 2011	Single	118	1/22	7/22	11/32	–	–	0/1	6/40	Age a
Current study 2012	Single	93	–	–	–	5/18	20/75	–	–	Soft tissue extension

^a Risk analysis performed using the whole patient population, including resections.

^b In the study, H₂O₂ was used as alternative to phenol.

A Center

B Total

C Resection ^c

D No adjuvants ^c

E Phenol + burr ^c

F PMMA ^c

G PMMA + phenol ^c

H PMMA + burr ^c

I PMMA + phenol + burr ^c

J Risk factors

^c Number of recurrences/total number of patients.