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. 2012 Aug 25;83(4):411–419. doi: 10.3109/17453674.2012.702388

Histomorphometry. Implant inserted press-fit in cancellous bone. Parathyroid hormone (PTH) treatment vs. control. Tissue fraction of bone, marrow–like tissue, and fibrous tissue at implant surface (surface fraction) and concentric region 0–500 μm, region 500–1,000 μm, and region 1,000–2,000 μm (volume fraction). n (PTH) = 8, n(control) = 9. Median (interquartile range)

Woven bone Lamellar bone Marrow Fibrous
Interface
  Control 11 (8–13) 6 (3–9) 84 (83–85) 0 (0–0)
  PTH 15 (13–18)a 3 (2–5) 80 (76–82)a 0 (0–0)
Region 0–500 μm
  Control 10 (4–13) 13 (5–16) 78 (77–80) 0 (0–0)
  PTH 14 (10–17) 8 (6–13) 75 (72–79) 0 (0–1)
Region 500–1,000 μm
  Control 4 (2–7) 20 (15–23) 74 (73–78) 0 (0–0)
  PTH 7 (5–12) 13 (12–22) 77 (74–80) 0 (0–0)
Region 1,000–2,000 μm
  Control 2 (1–3) 18 (16–20) 80 (79–82) 0 (0–0)
  PTH 3 (3–4)b 15 (11–16) b 83 (81–85) 0 (0–0)

a p < 0.05 (PTH compared to control). Mann-Whitney test.

b p = 0.07 within region (PTH compared to control). Mann-Whitney test.