Figure 4.
(A) Adrenal weights of male WT vs HSD1 KO/H6PDH KO/DKO animals. Mice were killed and adrenals were dissected and weighed. **P<0·01 (n>4/group) between WT and KOs. ##P<0·01 (n>4/group) between H6PDH KO and all other genotypes. (B) Adrenal weights of male WT vs 11β-HSD1 HET/H6PDH HET animals. Mice were killed and adrenals were dissected and weighed as in (A). **P<0·01 (n>4/group) between HSD1 KO/H6PDH HET and HSD1 HET/H6PDH KO vs all other genotypes. ##P<0·01 (n>4/group) between HSD1 HET/H6PDH KO vs all other genotypes.