Table 4.
Levels of interleukins pre- and postoperatively
Conventional (36 subjects) | MIO (32 subjects) | Average difference (95 % CI) | p Value | |
---|---|---|---|---|
IL-6 preoperatively | 39.57 ± 47.77 | 25.21 ± 29.73 | 14.37 (−5.19 to 33.92) | 0.1472 |
IL-6 postoperatively | 78.41 ± 67.04 | 39.02 ± 37.36 | 39.39 (12.65 to 66.13) | 0.0045 |
IL-8 preoperatively | 244.69 ± 476.18 | 248.57 ± 518.68 | −3.88 (−337.20 to 329.48) | 0.9813 |
IL-8 postoperatively | 32.88 ± 7.40 | 73.91 ± 105.47 | −41.04 (−87.70 to 5.63) | 0.0829 |
IL-10 preoperatively | 4.51 ± 3.19 | 2.89 ± 1.55 | 1.62 (0.38−2.86) | 0.0110 |
IL-10 postoperatively | 11.27 ± 19.74 | 8.90 ± 24.89 | 2.37 (−8.45 to 13.19) | 0.6634 |
TNF-α preoperatively | 30.56 ± 30.19 | 26.38 ± 19.19 | 4.18 (−8.39 to 16.76) | 0.5092 |
TNF-α postoperatively | 39.52 ± 55.13 | 23.44 ± 17.31 | 16.08 (−4.54 to 36.70) | 0.1241 |
The table shows the levels of interleukins IL-6, IL-8, IL-10, and TNF-α before and after operation and the comparison between the two groups; values are expressed in pg/ml. IL-6 level shows no significant difference between the two groups in the preoperative phase, whereas it becomes significant in the postoperative period (Student t test)