Fig. 2.

Example of the results from immunomonitoring. The results of patient 3007 who received two vaccinations and of whom blood was tested at week 0 (prevaccination; white), at week 7 (post-vaccination; black) and at week 9–11 (after LEEP excision; gray). The arrows indicate a preexisting response and the stars indicate a positive reaction during the course of the study. a Results of the IFNγ-ELISPOT assay. b Results of the proliferation assay showed no preexcising HPV-specific reactivity. c Cytokine bead array (CBA) was used to test the HPV16-specific production of the indicated cytokines measured in the culture supernatants of the proliferation assay. d DTH results showing clear redness and swelling of sites injected with E6.1, E6.2, E6.3, E6.4 and E7.2. e Overview of the IFNγ-ELISPOT results compared to the DTH skin test results