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. Author manuscript; available in PMC: 2012 Aug 26.
Published in final edited form as: Wiley Interdiscip Rev Syst Biol Med. 2010 Mar-Apr;2(2):148–161. doi: 10.1002/wsbm.53

Figure 4. evolution of RNA silencing machinery.

Figure 4

The evolutionary scenario for proteins involved in RNA-dependent gene silencing mechanisms is superimposed on the major developments in terms of small RNAs. Details on the architectures of proteins involved in the process can be found in the text. This scenario is based on the current state of comparative genomics and may require revisions as new eukaryotic species are sequenced.