Table 6.
Crude and adjusted associations between disc space narrowing, osteophytes and facet joint osteoarthritis (OA) with demographic, clinical and radiographic factors.
| Disc Space Narrowing | Osteophytes | Facet Joint OA | ||||
|---|---|---|---|---|---|---|
| Crude OR (95% CI) |
Adjusted OR* (95% CI) |
Crude OR (95% CI) |
Adjusted OR* (95% CI) |
Crude OR (95% CI) |
Adjusted OR* (95% CI) |
|
| Age 45-54 | Ref | Ref | Ref | Ref | Ref | Ref |
| 55-64 | 2.14 (1.52, 3.01) |
1.60
(1.11, 2.30) |
1.89 (1.33, 2.70) |
1.64
(1.12, 2.38) |
1.75 (1.24, 2.49) |
1.23
(0.83, 1.83) |
| 65-74 | 4.96 (3.43, 7.16) |
2.84
(1.88, 4.30) |
4.53 (3.09, 6.66) |
2.82
(1.82, 4.38) |
4.18 (2.80, 6.24) |
2.25 (1.39, 3.62) |
| 75+ | 7.55 (4.88, 11.65) |
3.07
(1.80, 5.24) |
5.14 (3.29, 8.03) |
3.14
(1.78, 5.54) |
9.30 (5.23, 16.56) |
2.98
(1.51, 5.88) |
|
| ||||||
| BMI <30 |
Ref | Ref | Ref | Ref | Ref | Ref |
| ≥30 | 1.00 (0.98, 1.02) |
0.86
(0.64, 1.15) |
1.46 (1.12, 1.90) |
1.55
(1.14, 2.09) |
1.33 (1.01, 1.75) |
1.56
(1.11, 2.19) |
|
| ||||||
| Race Caucasian | Ref | Ref | Ref | Ref | Ref | Ref |
| AA | 0.68 (0.53, 0.89) |
1.00
(0.74, 1.35) |
0.83 (0.63, 1.09) |
0.98
(0.72, 1.33) |
0.42 (0.31, 0.56) |
0.45 (0.32, 0.62) |
|
| ||||||
| Sex Female | Ref | Ref | Ref | Ref | Ref | Ref |
| Male | 0.76 (0.59, 0.99) |
0.68
(0.51, 0.92) |
1.94 (1.47, 2.56) |
2.68
(1.97, 3.63) |
0.66 (0.50, 0.88) |
0.75
(0.53, 1.05) |
|
| ||||||
| Low Back Symptoms |
1.44 (1.12, 1.85) |
1.37
(1.04, 1.80) |
1.28 (0.98, 1.66) |
1.11
(0.84, 1.48) |
1.05 (0.80, 1.38) |
0.84
(0.61, 1.15) |
|
| ||||||
| Knee OA | 1.94 (1.46, 2.58) |
1.16
(0.84, 1.59) |
2.45 (1.82, 3.30) |
1.62
(1.16, 2.27) |
2.69 (1.93, 3.74) |
1.69
(1.15, 2.49) |
|
| ||||||
| Hip OA | 1.20 (0.89, 1.62) |
0.99
(0.71, 1.38) |
1.31 (0.96, 1.79) |
1.01
(0.72, 1.43) |
1.23 (0.89, 1.72) |
0.89
(0.60, 1.31) |
|
| ||||||
| Hand OA | 2.63 (1.97, 3.52) |
1.14
(0.79, 1.63) |
2.00 (1.48, 2.69) |
0.81
(0.55, 1.18) |
4.55 (3.12, 6.63) |
1.67
(1.20, 2.28) |
Adjusted for all demographic, clinical, and the other radiographic variables in this table. Disc space narrowing and osteophyte estimates from proportional odds model and facet joint osteoarthritis from binary logistic model. Low back symptoms defined as pain aching or stiffness on most days. BMI=body mass index. OA=osteoarthritis. OR=odds ratio. CI= confidence interval. Ref=referent group. Knee and hip OA defined as Kellgren-Lawrence (K-L) score of 2-4. Hand OA defined as the presence of K-L grade 2-4 in at least one distal interphalangeal joint and 2 other interphalangeal joints or carpometacarpal joints.