Solvent accessible amino acid residues of albumin react with CBDP. The crystal structure of human albumin (Protein Data Bank code 1bmo) shows in sticks the 5 histidines, 5 lysines, and 2 tyrosines (plus Tyr-411) that are reactive towards CBDP. The structure was viewed with PyMOL software (DeLano, W.L. The PyMOL Molecular Graphics System (2002) DeLano Scientific, Palo Alto, CA, USA. http://www.pymol.org).