. Author manuscript; available in PMC: 2012 Aug 26.

Published in final edited form as: J Biol Chem. 1995 Jun 9;270(23):13987–13997. doi: 10.1074/jbc.270.23.13987

Table VI. CGS 21680-induced stimulation of cAMP production mediated by mutant A_2a adenosine receptors.

CGS 21680-stimulated cAMP production was examined in transiently transfected COS-7 cells in the presence of 0.1 mm rolipram as described under “Experimental Procedures.” In each case the maximal stimulation was 3–4-fold over control (see Fig. 5). Table shows mean ± S.E. of two or three independent experiments, each performed in duplicate.

Receptor	EC₅₀
	nm
wt (Tag3)	3.0 ± 1.0
I274A	100 ± 20
S277A	210 ± 35
H278A	920 ± 70

Table VI. CGS 21680-induced stimulation of cAMP production mediated by mutant A2a adenosine receptors.

Table VI. CGS 21680-induced stimulation of cAMP production mediated by mutant A_2a adenosine receptors.