. Author manuscript; available in PMC: 2013 Aug 17.

Published in final edited form as: Org Lett. 2012 Jul 31;14(16):4182–4185. doi: 10.1021/ol301847m

Table 2.

Survey of Halide and Pseudohalide Substrates^a


entry	X	yield^b
1	OCO₂tBu	15%
2	OPiv	44%
3	OTs	63%
4	OTf	4%
5	I	25%
6	Br	33%
7	Cl	98%

Conditions: NiCl₂(DME) (5 mol %), 3 (10 mol %), substrate (1 equiv), morpholine (1.8 equiv), Ph–B(pin) (0.35 equiv), NaOtBu (2.25 equiv), hexamethylbenzene (0.1 equiv), 3 h.

Yield determined by ¹H NMR analysis with hexamethylbenzene as internal standard.