Table 1.

Correlations between ventral midbrain iron and other phenotypes in the BXD panel

Phenotype	N	Citation	Control diet		ID diet
			Male	Female	Male	Female
Dopamine transporter protein density in ventral midbrain (F)	11	[18]	0.77**			0.78**
DRD2 protein density in the prefrontal cortex (M)	12	[18]	0.58*			0.71**
Anxiety assay, plus maze closed arm entries (M)	20	[29]	0.54*	0.52*
Anxiety assay, time in middle of elevated plus maze (M + F)	21	[29]			−0.56**
Depression assay, Porsolt behavioral despair test, time immobile (M)	19	[29]			−0.60**
Ethanol response, locomotion post-injection (2 g/kg ip)	15	[30]	−0.64*	−0.83***	−0.62*	−0.66**
Ethanol response, total ethanol intake in two-bottle choice	13	[13]		−0.74**		−0.61*
Max startle to 120 dB (M)	21	[29]			0.61**	0.69***
Iron in the prefrontal cortex	11	[20]	0.64*	0.68*
Hemoglobin, control diet (F)	24	Jellen et al. current				0.67***

The BXD phenotype database available on GeneNetwork.org allows comparison of a trait of interest with other phenotypes previously measured in the BXD panel. Selected correlations with VMB iron are reported here, as Pearson correlation coefficients

N number of strains in the comparison

^*p<0.05;

^**p<0.01;

^***p<0.001