. Author manuscript; available in PMC: 2012 Aug 26.

Published in final edited form as: Gene. 2008 Sep 18;427(1-2):51–57. doi: 10.1016/j.gene.2008.09.009

Table 1.

Mean numbers of synonymous (d_S) nonsynonymous (d_N) substitutions per site (± S.E.) in pairwise comparisons of non-repeat portions of the V regions within allelic families.

Allelic family	Comparison	d_S	d_N
3D7	1996	0.0021 ± 0.0021	0.0305 ± 0.0089^a
	2006	0.0009 ± 0.0007	0.0273 ± 0.0088^a
	1996 vs. 2006	0.0015 ± 0.0011	0.0297 ± 0.0093^a
FC27	1996	0.0013 ± 0.0013	0.0118 ± 0.0053
	2006	0.0024 ± 0.0023	0.0128 ± 0.0057
	1996 vs. 2006	0.0018 ± 0.0018	0.0123 ± 0.0055

Tests of the hypothesis that mean d_S equals mean d_N:

P < 0.01 (Z-test).