. Author manuscript; available in PMC: 2012 Aug 26.

Published in final edited form as: Gene. 2008 Sep 18;427(1-2):51–57. doi: 10.1016/j.gene.2008.09.009

Table 2.

Mean numbers of synonymous (p_S) nonsynonymous (p_N) differences per site (± S.E.) in pairwise comparisons of individual repeat units belonging to the FC27 allelic family.

Repeat Region	Comparison (no.)	p_S	p_N
R1	Same repeat type (6218)	0.0000 ± 0.0000	0.0005 ± 0.0001 ^a
	Different repeat type
	Same haplotype (6)	0.0000 ± 0.0000	0.0091 ± 0.0027 ^a,^b
	Different haplotype (446)	0.0000 ± 0.0000	0.0138 ± 0.0001 ^a,^b
R2	Same repeat type (24418)	0.0000 ± 0.0000	0.00185 ± 0.0002 ^a
	Different repeat type
	Same haplotype (724)	0.2984 ± 0.0118 ^b	0.2920 ± 0.0117 ^b
	Different haplotype (79969)	0.0000 ± 0.0000 ^b	0.0000 ± 0.0000 ^b

Tests of the hypothesis that mean p_S equals mean p_N:

P < 0.001 (randomization test).

Tests of the hypothesis that p_S or p_N equals the corresponding value for the same repeat type:

P < 0.001 (randomization test).