Table 4. GRPS-542: differentiation between schizophrenics and controls in four independent cohorts using a panel composed of all the nominally significant SNPs from ISC in the top candidate genes (542 SNPs in 42 genes).
GAIN EA | GAIN AA |
---|---|
P=0.03213, 527 SNPs in 41 genes were present in GAIN EA | P=0.00847, 516 SNPs in 42 genes were present in GAIN AA |
NonGAIN EA | NonGAIN AA |
P=0.00664, 537 SNPs in 42 genes were present in nonGAIN EA | P=0.03829, 537 SNPs in 42 genes were present in nonGAIN AA |
Abbreviations: AA, African American; EA, European American; GRPS, genetic risk prediction score; ISC, International Schizophrenia Consortium; SNP, single-nucleotide polymorphism.