Table 2.
The validity of the brief Community Screening Instrument for Dementia (CSI-D) informant scale, cognitive scale and combined algorithm, by region
| Region | AUROC | Optimal cutpoint | Sensitivity (%) | Specificity (%) | Youden's index |
|---|---|---|---|---|---|
| Brief CSI-D informant scale | |||||
| India | 0.97 (0.94–0.99) | >1 | 87.9 | 99.7 | 0.88 |
| China | 0.96 (0.93–0.98) | >1 | 82.3 | 98.3 | 0.81 |
| Latin America | 0.96 (0.95–0.97) | >1 | 94.7 | 92.6 | 0.87 |
| Nigeria | 1.00 (1.00–1.00) | >2 | 100 | 100 | 1.00 |
| Cuba (population) | 0.92 (0.90–0.94) | >1 | 76.4 | 93.1 | 0.70 |
| Brief CSI-D cognitive scale | |||||
| India | 0.91 (0.88–0.93) | <6/<7 | 72.4/86.5 | 93.5/81.8 | 0.66/0.68 |
| China | 0.92 (0.88–0.95) | <6/<7 | 81.3/94.5 | 95.1/67.4 | 0.75/0.62 |
| Latin America | 0.90 (0.88–0.92) | <6/<7 | 76.8/89.1 | 92.0/75.2 | 0.69/0.64 |
| Nigeria | 0.97 (0.94–1.00) | <6/<7 | 95.0/100.0 | 97.4/97.2 | 0.92/0.97 |
| Cuba (population) | 0.88 (0.85–0.90) | <6/<7 | 70.3/85.8 | 92.6/69.2 | 0.63/0.55 |
| Brief CSI-D combined scale | |||||
| India | 0.98 (0.90–0.99) | <5 | 97.3 | 90.5 | 0.88 |
| China | 0.99 (0.98–1.00) | <5 | 93.5 | 94.4 | 0.88 |
| Latin America | 0.97 (0.97–0.98) | <5 | 89.0 | 93.4 | 0.82 |
| Nigeria | 1.00 (1.00–1.00) | <5 | 100 | 100 | 1.00 |
| Cuba (population) | 0.94 (0.93–0.96) | <5/ <6 | 85.1/92.1 | 92.4/85.2 | 0.78/0.77 |