Table 2.
Characteristics of the entire cohort
| Experimental Group (n=50) | Control Group (n=51) | p | |
|---|---|---|---|
| Age (years old) | 41.9±6.3 | 42.8±8.5 | 0.548 |
| Gender (male/female) | 15/35 | 16/35 | 1.000 |
| Height (cm) | 160.3±5.8 | 160.1±7.2 | 0.878 |
| Weight (kg) | 51.7±7.5 | 52.2±8.5 | 0.755 |
| BSA (m2) | 1.57±0.14 | 1.59±0.16 | 0.506 |
| Basal INR | 0.94±0.11 | 0.91±0.09 | 0.136 |
| Baseline cardiac rhythm | 0.315 | ||
| Atrial fibrillation | 18 (36.0%) | 24(47.1%) | |
| Sinus rhythm | 32 (64.0%) | 27 (52.9%) | |
| Concomitant CAD | 2 (4.0%) | 4 (7.8%) | 0.678 |
| Ejection fraction (%) | 55.5±7.4 | 57.3±6.5 | 0.197 |
| Left atrial size (mm) | 51.6±6.3 | 50.3±7.2 | 0.337 |
| Operation | 0.831 | ||
| Single VR with/without CABG | 35 | 34 | |
| Double VR with/without CABG | 15 | 17 | |
| VKORC1(TT:TC:CC) | 44:6:0 | 41:9:1 | 0.528 |
| CYP2C9(*1/*1:*1/*3:*3/*3) | 48:2:0 | 49:2:0 | 0.951 |
BSA, body surface area; INR, international normalized ratio; CAD, coronary artery disease; VR, valve replacement.