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. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2012 Jun 12;159B(6):644–652. doi: 10.1002/ajmg.b.32068

Table 3.

Interactive effects of childhood adversity and 5-HTTLPR genotypes on PTSD risk based on logistic regression models.

	European American (n=2779)		African American (n=2339)
	OR (95%CI)	P-value	OR (95%CI)	P-value
Childhood adversity	4.87 (3.35–7.08)	<.0001	5.71 (4.02–8.10)	<.0001
5-HTTLPR	0.81 (0.62–1.06)	.13	1.14 (0.81–1.60)	.44
5-HTTLPR × Childhood adversity	1.49 (1.07–2.08)	.019	0.90 (0.60–1.35)	.62
Age	0.99 (0.98–0.99)	.0015	1.00 (0.99–1.02)	.55
Sex
Female	1.0
Male	0.49 (0.39–0.61)	<.0001	0.61 (0.48–0.78)	<.0001