Figure 8. CXCR2⁺ and MPO⁺ cells infiltrate spontaneous intestinal tumors.

Representative adenomas from Apc^min/+ and AhCreER;Apc^fl/+;Pten^fl/fl mice immunostained (brown) with Ab against CXCR2 (A) or MPO (B), counterstained with hematoxylin, and visualized by light microscopy. Tumors from AhCreER;Apc^fl/+;Pten^fl/fl tumors were harvested approximately 50 days after cre activation (4 i.p. injections of cre inducers). The boxed region in B is shown at higher magnification in the inset. Original magnification, ×200; ×400 (higher-magnification view).