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. Author manuscript; available in PMC: 2012 Aug 27.
Published in final edited form as: Synapse. 2010 Nov;64(11):829–838. doi: 10.1002/syn.20793

Figure 1. Estrogen treatment delays HIV-1 Tat 1-86 mediated decrease of cell viability in primary rat cortical cultures.

Figure 1

The graph demonstrates the decrease in live cells in primary cultures following exposure to 50 nM Tat 1-86. Addition of 10nM 17β-estradiol 24h prior to Tat 1-86 exposure was able to significantly delay onset of cell death in primary neuronal cultures. Data presented as mean values, n of sister cultures analyzed 5–10 per each time point. *P<0.05 as compared to non-treated controls, #P<0.05 as compared to Tat-treated vs. Tat+E treated cultures