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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: J Immunol. 2012 Jul 9;189(4):1737–1746. doi: 10.4049/jimmunol.1103541

Figure 2. TOLLIP polymorphisms and variation in mRNA expression.

Figure 2

Genomic DNA and mRNA were isolated from monocytes from 84 healthy individuals. TOLLIP mRNA expression was measured and normalized to GAPDH. Genotypes of six TOLLIP polymorphisms were examined for associations with TOLLIP mRNA expression. (rs5743899, AA = 49, AG = 31, GG = 4, Fig 2a; rs5743942, CC = 17, CT = 31, TT = 20, Fig 2b; ; rs3793964; CC = 36, CT = 24, TT = 16, Fig. 2c; rs3750920, CC = 26, CT = 32, TT = 16, Fig. 2d; rs3829223, CC = 19, CC = 32, TT = 27, Fig 2e; and rs3168046, CC = 15, CT = 22, TT = 14, Fig 2f). * p<0.01; # p=0.15, ANOVA analysis with Mann-Whitney test.