. Author manuscript; available in PMC: 2013 Jul 3.

Published in final edited form as: Langmuir. 2012 Jun 18;28(26):10033–10039. doi: 10.1021/la3010079

Table 2.

Summarized results with different procedures of biological Janus fabrication process. We conjugated BSA/SA and rIgG/SA to the Silica/Gold microparticles via APTES/Thiol-PEG-biotin cross-linking chemistry, which provided a range in processing yield.

Particle Surface	Cross-linking Chemistry	Process Yield
Carboxylated Polystyrene/Gold	EDAC/Amino-alkanethiol	< 5%
Biotin-conjugated Polystyrene/Gold	None/Amino-alkanethiol	11%
Silica/Gold	APTES/Amino-alkanethiol	< 5%
Silica/Gold	APTES/Thiol-PEG-biotin	90.5–98%