Figure 2. TRAMP^fmsmic-1 prostate tumors have lower histological grades.

Prostates of 15 TRAMP and 15 TRAMP^fmsmic-1 mice were excised at week 8 (panel A), 17 (panel B), 25 (panel C), and 33 (panel D). Serial sections were graded and scores for each grade were averaged for all the mice in the group. The graph represents the mean proportion of the prostate from all the mice in the group having each different pathologic grade, scored between 1 and 6± SEM. Numbers on the bars show number of mice in the group having a particular grade. p values are shown as *p<0.05; **p<0.01; ***p<0.001.