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. 2012 Aug 27;7(8):e43833. doi: 10.1371/journal.pone.0043833

Figure 4. MIC-1/GDF15 increases metastasis.

Figure 4

(A) Comparison between proportion of TRAMP (n = 30) and TRAMPfmsmic-1 (n = 30) mice having distant organ metastasis. The data is analyzed by Chi-square test. (B) Comparison between proportion of TRAMP (n = 59) and TRAMPfmsmic-1 (n = 33) mice with metastasis at 18–40 weeks, a period where TRAMP and TRAMPfmsmic-1 mice reach ethical end points at the same rate. The data is analyzed by Chi-square test. (C) Comparison between number of lung tumor colonies in MIC-1fms mice and control C57BL/6 mice injected intravenously with TC1-T5 cells. The data is analyzed by Unpaired t test. The p values for Chi-square test and Unpaired t test are shown as ***p<0.001.