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(A–D) Association results in the AA discovery set (A), a meta-analysis between the AA discovery and AA replication sets (B), the EA dataset (C), and a meta-analysis of the AA discovery, AA replication and EA datasets (D). The black horizontal line represents the threshold for genome-wide significance (P<5×10−8) and the gray line is the suggestive evidence of association threshold (P<1×10−4).
