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. 2012 Aug 27;7(8):e43907. doi: 10.1371/journal.pone.0043907

Table 3. Replication of previously reported SNPs associated with sarcoidosis [9], [11], [25], [27].

CHR BP(hg 19) SNP Gene Alleles1 African Americans European Americans PAll-Meta Heterogeneity Test
MAFAA-Disc 2 ORAA-Disc P AA-Disc MAFAA-Rep 2 ORAA-Rep P AA-Rep PAA-Meta MAFEA 2 OREA P EA Q I 2 (%)
6 32,363,816 rs2076530 BTNL2 T/C 0.309 0.84 2.50E-01 0.312 0.80 2.46E-02 2.42E-02 0.434 0.70 4.19E-06 1.44E-06 0.324 11.3
6 32,412,480 rs7194 HLA-DRA A/G 0.424 1.66 8.73E-09 0.445 1.40 3.44E-04 1.40E-11 0.395 1.35 1.26E-04 5.28E-14 0.304 16
6 32,429,643 rs9268853 HLA-DRB5 T/C 0.214 0.72 1.16E-03 0.197 0.86 2.03E-01 7.40E-04 0.331 0.76 9.79E-04 2.39E-06 0.544 0
6 32,574,171 rs615672 HLA-DRB1 C/G 0.449 0.64 1.23E-06 0.438 0.72 5.50E-04 2.60E-09 0.643 0.81 8.00E-03 9.97E-10 2.00E-07 93.5
6 57055354 rs1040461 RAB23 C/T 0.158 1.13 3.24E-02 0.177 1.21 1.18E-01 8.04E-03 0.079 0.89 4.18E-01 1.80E-01 0.257 26.4
10 81,926,702 rs1049550 ANXA11 G/A 0.185 0.68 7.91E-04 0.187 0.88 2.89E-01 8.46E-04 0.409 0.81 8.33E-03 2.30E-05 0.356 3.2
1

Major/minor allele of AAs as the reference;

2

Minor allele frequency;

3

The odds ratio (OR) was calculated with respect to the minor allele of AAs.