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. 2012 Aug 27;7(8):e43976. doi: 10.1371/journal.pone.0043976

Table 3. Variants of the glycosyltransferases involved in synthesis of LOS outer core structures in C. jejuni strains BD-07, BD-10, BD-39 and BD-67a.

Strains LOS class GeneBank Accession No. Cj1135 Cj1136 CgtAI CgtAII CgtB Cst-II GalTg
BD-07 A GU289927 One-domain Onb Mono-sialyl.c Absent Mono-sialyl. Mono-f Absent
BD-10 B GQ249164 Two-domain On Non-sialyl.d Offe Off Bi- Present
BD-39 A GU289928 One-domain On Mono-sialyl. Absent Mono-sialyl. Mono- Absent
BD-67 B GQ249165 Two-domain On Non-sialyl. Off Off Bi- Present
a

Assignment of the glycosyltransferase variants is based on amino acid sequence comparisons with variants of known specificities.

b

on: indicates that a gene has no frame-shift mutation.

c

Mono-sialyl.: the glycosyltransferase is specific for mono-sialylated acceptors.

d

Non-sialyl.: the glycosyltransferase is specific for non-sialylated acceptors.

e

off: indicates that a gene is inactive because of a frame-shift mutation.

f

Cst-II variants: mono-: monofunctional, Cst-II has α-2,3-sialyltransferase activity. bi-: bifunctional, Cst-II has both α-2,3-sialyltransferase and α-2,8-sialyltransferase activity.

g

GalT: β-1,4-galactosyltransferase that uses Glcβ-1,2-HepII- as acceptor.