Figure 3. Characterization of probands and families with multiple mutations.

A) Representative segregation of LIPG N396S and ABCA1 IVS24+1G>C mutations. Filled shape, HDLc<15^th percentile; empty shape, HDLc≥15^th percentile. B) HDLc levels of individuals with LIPG+/−ABCA1, LCAT, or LPL mutations. Individuals with LIPG mutations alone are described in Table 4. Individuals with single ABCA1, LCAT, and LPL mutations are from an independent Dutch-Caucasian population (Tables S1, S2, and S3 and data not shown). C) HDLc levels of individuals with mutations in LIPG, GALNT2, or LIPG+GALNT2. Individuals with single LIPG or GALNT2 mutations are described in Table 4.