Table 2. Factors associated with inadequate dosing of rifampin among patients treated with Rifater, Rifinah, or Rifampicin in single-drug preparation, 2007–2010, Taipei.
Adequate | Too high | Too low | |||
Number (%) | Relative RR | 95% CI | Relative RR | 95% CI | |
Weight (kg) | |||||
≤39 | 63(45.0%) | 1 | 1 | ||
40–49 | 576(72.8%) | 0.25 | 0.17–0.37 | 0.30 | 0.08–1.07 |
≥50 | 1932(97.3%) | 0.0002 | 0.00002–0.001 | 1.19 | 0.38–3.72 |
Preparations | |||||
Rifampicin | 459(83.0%) | 1 | 1 | ||
Rifater | 1663(89.9%) | 0.99 | 0.69–1.41 | 0.21 | 0.12–0.37 |
Rifinah150 | 102(77.9%) | 0.46 | 0.25–0.85 | 2.21 | 0.97–5.01 |
Rifinah300 | 347(90.4%) | 8.85 | 4.29–18.25 | 0.04 | 0.005–0.27 |
Adequate dosage (8–12 mg/kg) as the base for comparison. Too high, >12 mg/kg. Too low, <8 mg/kg. RR, risk ratio. CI, confidence interval.