Table 3. Factors associated with inadequate dosing of isoniazid among patients treated with Rifater, Rifinah or isoniazid in single-drug preparation, 2007–2010, Taipei.
Adequate | Too high | Too low | |||
Number (%) | Relative RR | 95% CI | Relative RR | 95% CI | |
Weight (kg) | |||||
≤39 | 19(13.3%) | 1 | 1 | ||
40–49 | 58(7.2%) | 2.64 | 1.36–5.14 | 0.44 | 0.06–3.43 |
≥50 | 706(35.1%) | 0.02 | 0.01–0.04 | 0.13 | 0.03–0.72 |
Preparations | |||||
Isoniazid | 406(68.8%) | 1 | 1 | ||
Rifater | 5(0.3%) | 12017.89 | 4215.91–34258.24 | 103.84 | 23.12–466.32 |
Rifinah150 | 25(19.1%) | 16.93 | 7.62–37.60 | 4.91 | 0.94–25.54 |
Rifinah300 | 347(90.4%) | 0.63 | 0.34–1.13 | 0.23 | 0.03–1.91 |
Adequate dosage (4–6 mg/kg) as the base for comparison. Too high, >6 mg/kg. Too low, <4 mg/kg. RR, risk ratio. CI, confidence interval.