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. 2012 Aug 27;7(8):e44133. doi: 10.1371/journal.pone.0044133

Table 3. Factors associated with inadequate dosing of isoniazid among patients treated with Rifater, Rifinah or isoniazid in single-drug preparation, 2007–2010, Taipei.

Adequate Too high Too low
Number (%) Relative RR 95% CI Relative RR 95% CI
Weight (kg)
≤39 19(13.3%) 1 1
40–49 58(7.2%) 2.64 1.36–5.14 0.44 0.06–3.43
≥50 706(35.1%) 0.02 0.01–0.04 0.13 0.03–0.72
Preparations
Isoniazid 406(68.8%) 1 1
Rifater 5(0.3%) 12017.89 4215.91–34258.24 103.84 23.12–466.32
Rifinah150 25(19.1%) 16.93 7.62–37.60 4.91 0.94–25.54
Rifinah300 347(90.4%) 0.63 0.34–1.13 0.23 0.03–1.91

Adequate dosage (4–6 mg/kg) as the base for comparison. Too high, >6 mg/kg. Too low, <4 mg/kg. RR, risk ratio. CI, confidence interval.