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ACE gene titration and pressor responses to angiotensins. A) Maximal pressor responses (ΔMBP, absolute variation of MBP) to angiotensin I (Ang I) or angiotensin II (Ang II) in ACE1c, ACE2c, or ACE3c mice under basal conditions. Area under curve (AUC) of pressor responses (absolute increases in MBP) vs. log dose Ang I; data are means ± se. *P < 0.05 vs. ACE2c.
