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Role of kinins in cardioprotection in ACE1c mice after IR injury. IR expressed as percentage of AR (IS/AR) was measured in ACE1c or ACE2c mice receiving saline (ACE1c, n=8; ACE2c, n=12) or the specific kinin B2 receptor antagonist, icatibant (ACE1c, n=4; ACE2c, n=5). Data are means ± se. *P < 0.05 vs. saline-ACE2c; †P < 0.001 vs. corresponding saline.
