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. Author manuscript; available in PMC: 2013 Sep 15.
Published in final edited form as: Gen Comp Endocrinol. 2012 Jul 25;178(3):562–572. doi: 10.1016/j.ygcen.2012.07.011

Summary of Developmental Defects in Lep and/or LepR Morphants

Body smaller, curved or kink body trunks, and larger yolk
Brain reduced differentiation of the dorsal optic tectum, dorsal cerebellum, and dorsal
hindbrain
Ear smaller otoliths and reduced semicircular canal structures
Eye smaller and reduced pigmentation; reduced retinal cells differentiation
Spinal cord thinner spinal nerves with less branching