. Author manuscript; available in PMC: 2013 Sep 30.

Published in final edited form as: Respir Physiol Neurobiol. 2012 Jul 11;183(3):211–217. doi: 10.1016/j.resp.2012.06.032

Table 2.

Comparison of baseline cardiorespiratory variables before and after intravenous DPDPE, U-50488H, histamine blockers, peripheral opioid receptor blocker and local injecting vehicle into the nodose ganglia.

		V_E (ml/min)	f (breaths/min)	V_T (ml)	T_E (s)	MBP (mmHg)	HR (beats/min)
DPDPE (iv) (n = 7)	Before	267 ± 34	97 ± 7	2.8 ± 0.2	0.39 ± 0.04	96 ± 7	315 ± 22
DPDPE (iv) (n = 7)	After	270 ± 39	103 ± 8	2.6 ± 0.3	0.38 ± 0.05	91 ± 8	311 ± 18
U-50488H (iv) (n = 7)	Before	238 ± 11	92 ± 8	2.6 ± 0.2	0.42 ± 0.04	94 ± 9	331 ± 17
U-50488H (iv) (n = 7)	After	210 ± 22 ^**	97 ± 8	2.1 ± 0.2 ^**	0.40 ± 0.05	96 ± 10	330 ± 9
NXM (iv) (n = 6)	Before	251 ± 19	98 ± 6	2.5 ± 0.3	0.39 ± 0.04	93 ± 6	329 ± 7
NXM (iv) (n = 6)	After	256 ± 21	102 ± 7	2.5 ± 0.3	0.36 ± 0.05	90 ± 7	332 ± 9
DPH/RTD (iv) (n = 6)	Before	216 ± 11	87 ± 6	2.5 ± 0.3	0.45 ± 0.05	82 ± 7	363 ± 19
DPH/RTD (iv) (n = 6)	After	235 ± 30^*	97 ± 7^*	2.4 ± 0.2	0.38 ± 0.03^**	92 ± 7^*	356 ± 29
Vehicle (local) (n = 5)	Before	231 ± 14	98 ± 7	2.4 ± 0.3	0.40 ± 0.05	98 ± 7	343 ± 17
Vehicle (local) (n = 5)	After	226 ± 21	93 ± 9	2.4 ± 0.3	0.42 ± 0.05	97 ± 8	341 ± 25

Data are shown as mean ± SE;

P < 0.05,

^**

P < 0.01 compared with “before”.

DPH/RTD, diphenhydramine/ranitidine; iv, intravenous; local, injection into the nodose ganglia; f, respiratory frequency; HR, heart rate; MBP, mean arterial blood pressure; NXM, naloxone methiodide; T_E, expiratory duration; V_E, minute ventilation; V_T, tidal volume.