Table 2.
Medians for demographic information and scores in neuropsychological background tests as a function of seizure lateralization.
| Max. score |
LMTLE patients (n = 16) | RMTLE patients (n = 10) | P value | |
|---|---|---|---|---|
| Mdn | Mdn | |||
| Age (years) | 46.0 | 35.5 | .076 | |
| Education (years) | 10.0 | 10.0 | .075 | |
| Age at disease onset (years) | 20.5 | 17.0 | — | |
| Disease duration (years) | 11.5 | 14.0 | — | |
|
| ||||
| Vocabulary [29] | 37 | 27.0 | 29.0 | .057 |
| Numeracy [30, 31] | 11 | 8.5* | 7.5* | .014 |
| Mental complex calculation [32] | 24 | 11.5 | 9.0 | .034 |
| Verbal memory (MGT) [33] | ||||
| Learning (5. trial) | 16 | 13.0 | 15.0 | — |
| Immediate free recall | 16 | 9.5* | 13.0 | — |
| Delayed free recall | 16 | 12.0 | 14.0 | — |
| Recognition (corrected score) | 16 | 15.0 | 14.0 | — |
| Nonverbal memory, immediate free recall (VVM) [34] | 31 | 17.5 | 17.0 | — |
| Anxiety (HADS-D) [35] | 21 | 5.5 | 7.0 | — |
| Depression (HADS-D) [35] | 21 | 4.5 | 2.0 | — |
|
| ||||
| Digit span forward (WMS-R) [36] | 12 | 7.0 | 6.0 | .079 |
| Digit span backward (WMS-R) [36] | 12 | 5.5 | 5.5 | .047 |
| Psychomotor speed (TMT-A) [37] | 29.5 | 24.5 | .691 | |
| Cognitive flexibility (TMT-B) [37] | 78.0 | 73.5 | .018 | |
| Categorical verbal fluency (RWT) [38] | 22.5 | 27.0 | .056 | |
| Phonological verbal fluency (RWT) [38] | 5.0* | 8.0 | .012 | |
| Set-shifting (RWT) [38] | 13.5 | 15.0 | .011 | |
| Categorization (WCST) [39] | ||||
| Completed categories | 5 | 3.5 | 2.0* | .027 |
| Perseverative errors | 10.0 | 10.0 | .032 | |
| Go-NoGo task (adapted from [40]) | ||||
| Correct Go-trials | 100 | 98.9 | 98.9 | .059 |
| Correct NoGo-trials | 100 | 83.3 | 98.6 | .878 |
| Planning (Planungstest) [41] | ||||
| Total number of moves | 35.5 | 36.0 | .029 | |
| Errors | 0.0 | 0.0 | — | |
Note: Group comparisons between LMTLE patients, RMTLE patients, and healthy controls were carried out by means of Kruskal-Wallis H-test. Significance was set at α = .05.
LMTLE: left-sided mesial temporal lobe epilepsy; RMTLE: right-sided mesial temporal lobe epilepsy; Mdn: Median; (*): slightly below cut-off or below the 10th percentile of normative data; (—): not available.