Table 2.
Change in seizure-like event amplitude, frequency, and length (% change) for the three groups after 60 minutes of aconitine perfusion. Data are median (95% confidence interval).
| WT (n = 12, 3 animals) |
WT + mefloquine (n = 12, 3 animals) |
Cx36 KO (n = 14, 3 animals) |
P value | |
|---|---|---|---|---|
| Amplitude (% change) | −37 (−54–−26) | −48 (−64–−25) | −49 (−61–5) | .76 |
| Length (% change) | −28 (−50–1) | −37 (−61–−27) | −46 (−66–9) | .50 |
| Frequency (% change) | 900 (657–1272) | 557 (322–737) | 640 (416–1284) | .13 |
WT: wild-type.
Cx36 KO, connexin36 knockout.
P-values from Kruskal-Wallis test (nonparametric ANOVA) comparing the % change across all three groups.