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. 2011 Mar 6;2011:758407. doi: 10.1155/2011/758407

Table 1.

Clinical history, MRI findings, pathological diagnosis, and postoperative outcome of 10 patients who underwent selective amygdalohippocampectomy.

Case no. Age/sex MRI findings Pathological diagnosis of hippocampus AED medication Type of seizures Years with epilepsy No. seizures/month
1a, b, c 21/M MTS, left mild gliosis, focal neuronal loss LTG, LEV SPS, CPS 19 30
2 a, b, c 26/F MTS, right mild gliosis, severe neuronal loss CBZ, GP, LEV CPS, SGS 10 8
3 a, b, c 28/F MTS, left marked gliosis, severe neuronal loss (Wyler II)f OXC, LTG, PHT SPS, CPS, SGS 26 2
4 a, b, c 27/M MTS, right marked gliosis, severe neuronal loss (Wyler II) LTG, LEV CPS, SGS 25 4
5 a, b, c 34/F MTS, left marked gliosis, severe neuronal loss (Wyler III) LEV, PB SPS, CPS, SGS 32 6
6 b, c 40/F MTS, left marked gliosis, focal mild neuronal loss VPA, LEV CPS, SGS 18 12
7 b, c 68/F MTS, right marked gliosis, severe neuronal loss LTG, LEV SPS, CPS 43 4
8 b, c 22/M MTS, right marked gliosis, severe neuronal loss (Wyler IV) CBZ, GP, LEV SPS, CPS, SGS 18 4
9 d, e 41/M MTS, right marked gliosis, severe neuronal loss (Wyler IV) CBZ, VPA, TPM SPS, CPS, SGS 6 2
10 d, e 41/F MTS, left marked gliosis, severe neuronal loss CBZ, LEV, PHT SPS, CPS, SGS 20 2

AEDs: antiepileptic drugs; CBZ: carbamazepine; LEV: levetiracetam; LTG: lamotrigine; PHT: phenytoin; TPM: topiramate; GP: gabapentin; PB: phenobarbital; OXC: oxcarbazepine; VPA: valproic acid.

SPS: simple partial seizures; CPS: complex partial seizures; SGS: secondary generalized seizures.

aImmunohistochemistry.

bOne-cycle target labelling gene array.

cQuantitative real-time RT-PCR (TaqMan).

dBrain-derived microvascular endothelial cells (MVECs).

eTwo-cycle target labeling gene array.

fWyler classification was not determined in all cases.

MTS, mesial temporal sclerosis.